Equine Coli Endoto
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Equine Coli Endoto

Equine Coli Endotox, 1 dose x 10 ml SKU: 060NOV01-10 [printable] INDICATIONS: For use in newborn foals as an aid in the prevention of colibacillosis and septicemia caused by K99 piliated Escherichia coli . • Immediate Protection — Equine Coli Endotox goes to work immediately, eliminating doubt that newborn foals ingested adequate levels of the antibody to ward off deadly E. coli . • Broad Spectrum Effectiveness — Equine Coli Endotox provides protection against systemic E. coli infection (septicemia) in newborns. In studies conducted by research scientists at Novartis, 100 percent of foals treated with Equine Coli Endotox were protected against death following severe E. coli challenge. • Safe — Donor horses which generate the antibody in Equine Coli Endotox are routinely tested to be free of equine infectious anemia, glanders, brucellosis, and equine viral arteritis. DIRECTIONS: Shake well before using. Administer 10 mL orally to foals less than 12 hours old. Slowly syringe towardthe back of the foal"s mouth. Colostrum should be fed to each foal. PRECAUTIONS: Store out of direct sunlight at 2°-7° C (35°-45° F). DO NOT FREEZE. Use entire contents when first opened. Anaphylactic reactions may occur. Symptomatic treatment: Epinephrine. Contains oxytetracycline, phenol, and thimerosal as preservatives. TECHNICAL DISEASE INformATION: Endotoxemia, septicemia, and enteric infections are the most severe problems affecting neonatal foals, often ulminating in death. Approximately 25 percent of all septicemias in foals are caused by Escherichia coli . nvasive strains of this bacteria enter the foal's bloodstream either through the intestinal tract, the respiratory tract, or the umbilical cord. Bacteria begin to circulate throughout the body, releasing toxins and causing symptoms, such as lethargy, depression, anorexia and sudden death. Septicemia in foals often results in chronic arthritis, since the bacteria tend to take refuge in the joint cavities where they are difficult to reach with antibiotics. Foals with E. coli infection may also show diarrhea, but this is less common than in other species such as calves and piglets. The most common factor predisposing foals to developing E. coli septicemia is hypogammaglobulinemia (inadequate levels of passive antibody protection from the mare's colostrum). This is caused by several factors, such as foals failing to nurse adequately, poor quality colostrum in the mare, or loss of colostrum prior to foaling in mares that leak milk. Up until now, measures to combat this problem were limited to complex procedures such as blood transfusions from mare to foal, or obtaining colostrum from another mare to feed to the foal. Sinc
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